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HPLC Columns

Thermo Fisher Scientific manufactures innovative separation materials for a wide range of applications in a global marketplace, including HypersilTM, HypercarbTM, BioBasicTM and HyPURITYTM columns. We offer our customers a broad choice of quality HPLC columns, premium phases and innovative hardware designs to meet your application needs. 


Columns in this category are optimized for the separation of peptides, proteins and other biomolecules.

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These phases are globally referenced original columns manufactered by Thermo Fisher Scientific, including Hypersil, Hypersil BDS and BETASIL columns.  For new methods, we recommend the use of one of our Premium Columns, especially Hypersil GOLD columns for outstanding peak shape.

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To extend the life of your analytical column, consider using guard columns or cartridges. 

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For HPLC columns that operate beyond the typical pH range of 2 to 8, choose one of these. Hypercarb columns can be used from pH 0 to 14.

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High performance liquid chromatography columns containing solid core particles with an porous outer layer that enable high speed, high efficiency separations at low backpressures.

A broad choice of quality HPLC columns, premium phases and innovative hardware designs to meet your application needs.

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Guard cartridges containing solid core particles with an porous outer layer that enable high speed, high efficiency separations at low backpressures.

A broad choice of quality HPLC columns, premium phases and innovative hardware designs to meet your application needs.

Accucore HPLC Columns 

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This category includes column for anion and cation exchange as well as mixed-mode analyses. 

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Thermo Fisher Scientific offers many columns and accessories for your LC/MS system, including hardware designs to optimize connectivity, speed, sensitivity, ionization technique and sample size.

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Thermo Fisher Scientific has several phases that are designed for the retention of polar compounds, or offer alternative selectivity to traditional HPLC phases.

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This category of columns are guaranteed to give sharp peak shapes, high peak capacities and sensitivity in the the most demanding method development circumstances. 

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To determine molecular mass or molecular weight distribution, choose a SEC column. 

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