The new MALDI LTQ Orbitrap series simplifies the analysis of whole tissue, biological and polymer samples by eliminating sample preparation. The new MALDI source, available on the LTQ Orbitrap XL and Discovery, is ideally suited for proteomics and metabolism applications. Resolution of greater than 50,000 FWHM and mass accuracies of 2 ppm are available for MS, MS/MS and even MSn data.
Using the high resolving power and outstanding mass accuracy of the LTQ Orbitrap, researchers can now perform peptide and protein identification of MALDI-produced ions.
Other important applications include the high-throughput analysis of in-gel digests of 2D gel spots, de novo sequencing, iTRAQ™ quantitation, tissue imaging and small molecule analysis. more ... | The LTQ Orbitrap XL ETD is the only ETD instrument with both high resolution and accurate mass, enabling definitive protein characterization. Thermo Scientific ETD technology enables highly sensitive post-translational modification analyses. Combined with the LTQ Orbitrap XL, ETD completes the most advanced proteomics platform available by offering three complementary fragmentation techniques in one instrument:
CID, HCD and ETD for definitive protein/peptide characterization, post-translational modification (PTM) analysis (especially phosphorylation); and top-down or middle-down sequencing of proteins and peptides. more ... |
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